Project Details:

Recommendations for the use of nanotechnology in clinical laboratories

To provide recommendations for the use of emerging nanotechnology in the clinical setting. Nanotechnology will offer an increased spectrum of sophisticated chemical markers at the point of care and high capacity measurements in the central laboratory.

The technology that employs micro fabricated devices for biomedical applications i.e. using sample and reagents in minute amounts e.g. nanoliter range, has seen an almost exponential growth. The potential of this technology for analytical purposes in biomedicine has been demonstrated for immunoassays, the polymerase chain reaction (PCR), cell isolation, electrophoresis and mass spectrometry. This technology will also offer large scale screening possibilities for a wide range of analytes and be applicable outside the traditional laboratory through the introduction of robust and simplified instruments. The recommendations will address issues related to traceability of calibrators, transferability of results and other data performance specifications and quality assessment

Project completed - IUPAC Technical Report published in Pure Appl. Chem. 78(3), 677-684, 2006
+- errata (Pure Appl. Chem. 78(5), 1091, 2006)

• Wilding, Peter

• Kricka, Larry