Project Details:

Human Drug Metabolism Database (hDMdb)

Long term: To ultimately mount this database on the www so that it can be readily accessed and utilized by scientists around the world.

Immediate term: (i) To elaborate a detailed outline for the db that can be published and used within future grant applications to other funding sources which can then provide the significantly larger amounts of financing needed to actually reach the long term goal; and (ii) Set-up a working prototype on a common desk-top platform using one of today’s inexpensive software systems which have now evolved to be able to handle dbs of this size.

This topic has previously been an IUPAC Project, namely 2000-010-1-700. Previous efforts led to a specific software-dependent outline accompanied by an attempt to devise a working prototype using Oracle. The legally cumbersome and expensive Oracle db shell is no longer needed for this type of undertaking (see immediate objectives noted above). The informational content of the db will remain the same as that proposed in the original submission which did include, even at that earlier point in time, a connected ‘bin’ for organizing genetic information relevant to human DM considerations.

Jan 2012 - project announcement published in Chem. Int. Jan-Feb 2012, p. 22

• Erhardt, Paul

• Sarver, Jeffrey
• Trendel, Jill