Project Details:

Medicinal Chemistry Curriculum

Project No.:761-1-90
Start date:1990-01-01
End date:2000-12-31
Division:
Objective:
The objective is to examine how best to structure a medicinal chemistrycurriculum with regard to subject matter, sequence and emphasis, recognizingthe fact that the pharmaceutical industry is by far the largest employerof medicinal chemists. Account will be taken of the different situationsexisting in different countries.
Description:
No description available.
Progress:
A questionnaire was sent to research companies in various countries.Replies were analyzed and results given in talks at National Symposiain the Netherlands and Italy, and published: W.-D. Busse and C.R. Ganellin,Trends in Drug Research, 1993, 20, 305. US data are in C.R. Ganellinet al, Ann Rep Med Chem. vol 30, 329, and full data are in Busseet al, Eur J Med Chem. 1996, 31, 747. The results support shortcourses for teaching the elements of medicinal chemistry as one-weeksummer schools in UK, USA, Netherlands and Switzerland. Curriculum recommendationshave been published by Ganellin, ChemInt. 1995, 17,212. A follow up questionnaire has been sent to University Deptsthat teach medicinal chemistry.

The results of this follow-up questinnaire have been publishedin the European Journal of Medicinal Chemistry, 2000, 35,163-174; article entitled "Universityeducation of medicinal chemists: comparison of eight countries",and prepared by C R Ganellin, LA Mitscher, B Clement, T-H Kokayashi,E Kyburz, O Lafont, A Marcincal, A Monge, G Tarzia and JG Topliss.

Part of the investigation has been published in the followingtwo references:

  • Education of Medicinal Chemists in Departments of Medicinal Chemistry(USA)
    Medicinal Research Reviews    , 1998, 18, 121-137
    C.R. Ganellin, L.A. Mitscher and J.G. Topliss
  • Medicinal Chemistry Graduate School Curriculum and Contributionto Pharmaceutical Industry in Japan
    Med. Chem. News    , 1998, 8 (4), 21-28
    T-H. Kobayashi and C.R. Ganellin
    Reprint in ChemInt. 1999,21, 138.

Project completed - Final report entitled 'TwoRoutes to Becoming a Medicinal Chemist' is published in Chem.Int.2001, 22(3), 43-45