Pure Appl. Chem., 2002, Vol. 74, No. 1, pp. 11-17
Functionalized main-group organometallics for organic synthesis
Abstract: Highly functionalized Grignard-reagents can be easily obtained by an iodinemagnesim exchange reaction and further reacted with various electrophiles. Via a BZn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.