Pure Appl. Chem., 2003, Vol. 75, No. 10, pp. 1443-1451
doi:10.1351/pac200375101443
Birch reduction and its application in the total synthesis of natural products*
G.S.R. Subba Rao
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India
Abstract:
The unique availability of substituted cyclohexa-1,4- and 1,3-dienes, notably enol ethers, from Birch reduction of anisoles, permits many novel synthetic reactions of general utility. The total synthesis of several natural products derived from polyketides have been accomplished using a Diels–Alder and Alder–Rickert process. The strategies of the synthesis are discussed.
*Lecture presented at the 4th Florida Heterocyclic Conference, Gainesville, Florida, 10-12 March 2003. Other presentations are published in this issue, pp. 1403-1475.
All articles from the 4th Florida Heterocyclic Conference, Gainesville, Florida, USA, 10–12 March 2003.