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Pure Appl. Chem., 2003, Vol. 75, No. 2-3, pp. 209-221

doi:10.1351/pac200375020209

New and old challenges in total synthesis. From concept to practice*

S. Hanessian, R. Margarita, A. Hall, S. Johnstone, M. Tremblay, and L. Parlanti

Department of Chemistry, Université de Montréal, P.O. Box 6128, Station Centre-ville, Montréal, P.Q., H3C 3J Canada


Abstract: The total synthesis of dysinosin A, a novel member of the aeruginosin group of marine natural products is discussed. The stereocontrolled synthesis also confirms the proposed structure and absolute stereochemistry of the natural product.