Pure Appl. Chem., 2006, Vol. 78, No. 2, pp. 241-247
doi:10.1351/pac200678020241
Photochemical release of various functional groups*
Christian G. Bochet
Department of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland
Abstract:
The photochemical liberation of functional groups is an attractive alternative to the traditional chemical approach. Several photolabile protecting groups have been developed in the past decades, but they were mainly designed to protect amines and carboxylic acids. In this account, we present some of our recent work on the photochemical release of other functions, such as silanols, aldehydes, and ketones. We also describe a new form of differentiation among several photolabile groups by the use of monochromatic light tuned to each of them: the chromatic orthogonality.
Keywords: chromatic orthogonality; photochemistry; protecting groups.
*Pure Appl. Chem. 78, 197-523. An issue of reviews and research papers based on lectures presented at the 13th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS-13), Geneva, Switzerland, 17-21 July 2005.