Pure Appl. Chem., 2006, Vol. 78, No. 2, pp. 391-396
doi:10.1351/pac200678020391
Chiral Ru/PNNP complexes in catalytic and stoichiometric electrophilic O- and F-atom transfer to 1,3-dicarbonyl compounds*
Cristina Bonaccorsi, Martin Althaus, Claus Becker, Antonio Togni, and Antonio Mezzetti
Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093 Zürich, Switzerland
Abstract:
The asymmetric hydroxylation and fluorination catalyst [Ru(OEt2)2(PNNP)]2+ (PNNP = chiral tetradentate ligand with a P2N2 donor set) reacts with 1,3-dicarbonyl compounds to give dicationic adducts and, upon deprotonation, the corresponding enolato complexes. The relevance of these species to catalytic O- and F-transfer is investigated.
Keywords: 1,3-dicarbonyl compounds; asymmetric catalysis; fluorination; hydroxylation; ruthenium.
*Pure Appl. Chem. 78, 197-523. An issue of reviews and research papers based on lectures presented at the 13th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS-13), Geneva, Switzerland, 17-21 July 2005.