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Pure Appl. Chem., 2008, Vol. 80, No. 3, pp. 609-620

http://dx.doi.org/10.1351/pac200880030609

Diversity-oriented syntheses of functional π-systems by multicomponent and domino reactions

Thomas J. J. Müller1 and Daniel M. D'Souza2

1 Institute for Organic Chemistry and Macromolecular Chemistry, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, D-40225 Düsseldorf, Germany
2 School of Chemistry, The University of Edinburgh, The King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK

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  • García-Melchor Max, Pacheco María C., Nájera Carmen, Lledós Agustí, Ujaque Gregori: Mechanistic Exploration of the Pd-Catalyzed Copper-Free Sonogashira Reaction. ACS Catal 2012, 2, 135. <http://dx.doi.org/10.1021/cs200526x>
  • Teiber Marco, Müller Thomas J. J.: Rapid consecutive three-component coupling-Fiesselmann synthesis of luminescent 2,4-disubstituted thiophenes and oligothiophenes. Chem Commn 2012, 48, 2080. <http://dx.doi.org/10.1039/c2cc17548g>
  • Sharma Sudhir K., Mandadapu Anil K., Kumar Brijesh, Kundu Bijoy: Synthesis of Iodo-Indoloazepinones in an Iodine-Mediated Three-Component Domino Reaction via a Regioselective 7-endo-dig Iodo-Cyclization Pathway±CDRI Communication No. 8094. J Org Chern 2011, 76, 6798. <http://dx.doi.org/10.1021/jo201228t>
  • Willy Benjamin, Müller Thomas J. J.: Rapid One-Pot, Four-Step Synthesis of Highly Fluorescent 1,3,4,5-Tetrasubstituted Pyrazoles§. Org Lett 2011, 13, 2082. <http://dx.doi.org/10.1021/ol2004947>
  • Muschelknautz Christian, Frank Walter, Müller Thomas J. J.: Rapid Access to Unusual Solid-State Luminescent Merocyanines by a Novel One-Pot Three-Component Synthesis. Org Lett 2011, 13, 2556. <http://dx.doi.org/10.1021/ol200655s>
  • Chen Xiaopeng, Wang Hongbo, Jin Xiaohan, Feng Jinwu, Wang Yanguang, Lu Ping: Palladium catalyzed bicyclization of 1,8-diiodonaphthalene and tertiary propargylic alcohols to phenalenones and their applications as fluorescent chemosensor for fluoride ions. Chem Commun 2011, 47, 2628. <http://dx.doi.org/10.1039/c0cc04875e>
  • Schönhaber Jan, Müller Thomas J. J.: Luminescent bichromophoric spiroindolones – synthesis and electronic properties. Biomol Chem 2011, 9, 6196. <http://dx.doi.org/10.1039/c1ob05703k>
  • Grotkopp Oliver, Ahmad Atia, Frank Walter, Müller Thomas J. J.: Blue-luminescent 5-(3-indolyl)oxazoles via microwave-assisted three-component coupling–cycloisomerization–Fischer indole synthesis. Biomol Chem 2011, 9, 8130. <http://dx.doi.org/10.1039/c1ob06153d>
  • Willy Benjamin, Müller Thomas J. J.: Three-component synthesis of benzo[b][1,5]thiazepines via coupling–addition–cyclocondensation sequence. Mol Divers 2010, 14, 443. <http://dx.doi.org/10.1007/s11030-009-9223-z>
  • Chamas Zein el abidine, Dietz Olivier, Aubert Emmanuel, Fort Yves, Mamane Victor: Synthesis of new pentacyclic chromophores through a highly regio- and diastereoselective cascade process. Org Biomol Chem 2010, 8, 4815. <http://dx.doi.org/10.1039/c0ob00390e>
  • Merkul Eugen, Oeser Thomas, Müller Thomas J. J.: Consecutive Three-Component Synthesis of Ynones by Decarbonylative Sonogashira Coupling. Chem Eur J 2009, 15, 5006. <http://dx.doi.org/10.1002/chem.200900119>
  • Carpita Adriano, Ribecai Arianna: Convenient copper- and solvent-free Sonogashira-type alkynylation of aryl iodides and bromides using Pd EnCat™. Tetrahetron Lett 2009, 50, 204. <http://dx.doi.org/10.1016/j.tetlet.2008.10.130>
  • Mueller Thomas J. J., D'Souza Daniel M.: ChemInform Abstract: Diversity-Oriented Syntheses of Functional π-Systems by Multicomponent and Domino Reactions. ChemInform 2008, 39. <http://dx.doi.org/10.1002/chin.200832249>
  • Willy Benjamin, Müller Thomas J. J.: Regioselective Three-Component Synthesis of Highly Fluorescent 1,3,5-Trisubstituted Pyrazoles. Eur J Org Chem 2008, 2008, 4157. <http://dx.doi.org/10.1002/ejoc.200800444>
  • Willy Benjamin, Dallos Timea, Rominger Frank, Schönhaber Jan, Müller Thomas J. J.: Three-Component Synthesis of Cryofluorescent 2,4-Disubstituted 3H-1,5-Benzodiazepines - Conformational Control of ­Emission Properties. Eur J Org Chem 2008, 2008, 4796. <http://dx.doi.org/10.1002/ejoc.200800619>
  • D'Souza Daniel M, Müller Thomas J J: Catalytic alkynone generation by Sonogashira reaction and its application in three-component pyrimidine synthesis. UNKNOWN 2008, 3, 1660. <http://dx.doi.org/10.1038/nprot.2008.152>