Pure Appl. Chem., 2008, Vol. 80, No. 5, pp. 831-844
doi:10.1351/pac200880050831
Organometallic catalysts in synthetic organic chemistry: From reactions in aqueous media to gold catalysis*
Jean-Pierre Genêt, Sylvain Darses, and Véronique Michelet
Selective Organic Synthesis and Natural Products Laboratory, Ecole Nationale Supérieure de Chimie de Paris, UMR CNRS 7573, 11 rue P. et M. Curie, 75231 Paris Cedex 05, France
Abstract:
Water has attracted significant attention as an alternative solvent for transition-metal-catalyzed reactions. The use of water as solvent allows simplified procedures for separation of the catalyst from the products and recycling of the catalyst. Water is an inexpensive reagent for the formation of oxygen-containing products such as alcohols. The use of water as a medium for promoting organometallic and organic reactions is also of great potential. This chapter will focus on old and recent developments in the design and applications of some catalytic reactions using aqueous-phase Pd, Rh, Pt, and Au complexes.
Keywords: asymmetric 1,4-addition; catalysis; gold; palladium; potassium organotrifluoroborates; recycling; rhodium; water.
*Paper based on a presentation at the 14th International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis (OMCOS-14), 2-6 August 2007, Nara, Japan. Other presentations are published in this issue, pp. 807-1194.