| Number: | 2004-025-1-700 |
|---|---|
| Start: | 01 September 2004 |
| End: | 24 January 2007 |
To provide a compendium of the biological targets of the top 100 drugs.
A recent article (Fixing the Drugs Pipeline, The Economist March 11 2004) indicated that the 100 best selling target 43 gene products. However there does not appear to be a resource where compiled target information is readily available in a single source. The intention is to provide a resource containing the following information on commercially important drug targets: type of target (enzyme, receptor etc); brief description of relevance to disease treated; reference to knockout information, if available; reference to structural information, if available; listing of the marketed drugs that interact with the target along with potency and relevant selectivity information.