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Pure Appl. Chem. 75(2-3), 251-258, 2003

Pure and Applied Chemistry

Vol. 75, Issue 2-3

Total syntheses of 11-deoxytetrodotoxin and 8,11-dideoxytetrodotoxin

T. Nishikawa, D. Urabe, K. Yoshida, T. Iwabuchi, M. Asai, and M. Isobe

Laboratory of Organic Chemistry, Graduate School of Bioagricultural Sciences,
Nagoya University, Chikusa, Nagoya 464-8601, Japan

Abstract: 11-Deoxytetrodotoxin and 8,11-dideoxytetrodotoxin were synthesized from the same intermediate in the enantiomerically pure form.

*Pure Appl.Chem. 75, 141�419 (2003). An issue of reviews and research papers based on lectures presented at the 23rd IUPAC International Symposium on the Chemistry of Natural Products, Florence, Italy, 28 July � 2 August 2002.


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