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Pure Appl. Chem., 1999, Vol. 71, No. 6, pp. 1089-1094

http://dx.doi.org/10.1351/pac199971061089

Finding the needle in the haystack. The dereplication of natural product extracts

G. A. Cordell and Y. G. Shin

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  • Klitgaard Andreas, Iversen Anita, Andersen Mikael R., Larsen Thomas O., Frisvad Jens Christian, Nielsen Kristian Fog: Aggressive dereplication using UHPLC–DAD–QTOF: screening extracts for up to 3000 fungal secondary metabolites. Anal Bioanal Chem 2014, 406, 1933. <http://dx.doi.org/10.1007/s00216-013-7582-x>
  • Samat Norazwana, Tan Pei Jean, Shaari Khozirah, Abas Faridah, Lee Hong Boon: Prioritization of Natural Extracts by LC–MS-PCA for the Identification of New Photosensitizers for Photodynamic Therapy. Anal. Chem. 2014, 86, 1324. <http://dx.doi.org/10.1021/ac403709a>
  • Seiber James N., Molyneux Russell J., Schieberle Peter: Targeted Metabolomics: a New Section in the Journal of Agricultural and Food Chemistry. J. Agric. Food Chem. 2014, 62, 22. <http://dx.doi.org/10.1021/jf4046254>
  • Xie Pengfei, Ma Ming, Rateb Mostafa E., Shaaban Khaled A., Yu Zhiguo, Huang Sheng-Xiong, Zhao Li-Xing, Zhu Xiangcheng, Yan Yijun, Peterson Ryan M., Lohman Jeremy R., Yang Dong, Yin Min, Rudolf Jeffrey D., Jiang Yi, Duan Yanwen, Shen Ben: Biosynthetic Potential-Based Strain Prioritization for Natural Product Discovery: A Showcase for Diterpenoid-Producing Actinomycetes. J. Nat. Prod. 2014, 77, 377. <http://dx.doi.org/10.1021/np401063s>
  • Roldán Cristina, de la Torre Angel, Mota Sonia, Morales-Soto Aránzazu, Menéndez Javier, Segura-Carretero Antonio: Identification of active compounds in vegetal extracts based on correlation between activity and HPLC–MS data. Food Chemistry 2013, 136, 392. <http://dx.doi.org/10.1016/j.foodchem.2012.08.027>
  • Seger Christoph, Sturm Sonja, Stuppner Hermann: Mass spectrometry and NMR spectroscopy: modern high-end detectors for high resolution separation techniques – state of the art in natural product HPLC-MS, HPLC-NMR, and CE-MS hyphenations. Nat. Prod. Rep. 2013, 30, 970. <http://dx.doi.org/10.1039/c3np70015a>
  • Dias Daniel A., Urban Sylvia, Roessner Ute: A Historical Overview of Natural Products in Drug Discovery. Metabolites 2012, 2, 303. <http://dx.doi.org/10.3390/metabo2020303>
  • Cordell Geoffrey A.: Phytochemistry and traditional medicine – A revolution in process. Phytochem Lett 2011, 4, 391. <http://dx.doi.org/10.1016/j.phytol.2011.05.005>
  • Nielsen Kristian F., Månsson Maria, Rank Christian, Frisvad Jens Christian, Larsen Thomas O.: Dereplication of Microbial Natural Products by LC-DAD-TOFMS. Journal of Natural Product 2011, 74, 2338. <http://dx.doi.org/10.1021/np200254t>
  • Alali Feras Q., Tawaha Khaled: Dereplication of bioactive constituents of the genus hypericum using LC-(+,−)-ESI-MS and LC-PDA techniques: Hypericum triquterifolium as a case study. Saudi Pharmaceutical Journal 2009, 17, 269. <http://dx.doi.org/10.1016/j.jsps.2009.10.002>
  • Jarussophon Suwatchai, Acoca Stephane, Gao Jin-Ming, Deprez Christophe, Kiyota Taira, Draghici Cristina, Purisima Enrico, Konishi Yasuo: Automated molecular formula determination by tandem mass spectrometry (MS/MS). Analyst 2009, 134, 690. <http://dx.doi.org/10.1039/b818398h>
  • Cordell Geoffrey A., Colvard Michael D.: Some thoughts on the future of ethnopharmacology. Journal of Ethanopharmacology 2005, 100, 5. <http://dx.doi.org/10.1016/j.jep.2005.05.027>
  • Pauli Guido F., Case Ryan J., Inui Taichi, Wang Yuehong, Cho Sanghyun, Fischer Nikolaus H., Franzblau Scott G.: New perspectives on natural products in TB drug research. Life Sci Oxford 2005, 78, 485. <http://dx.doi.org/10.1016/j.lfs.2005.09.004>
  • Balunas Marcy J., Kinghorn A. Douglas: Drug discovery from medicinal plants. Life Sci Oxford 2005, 78, 431. <http://dx.doi.org/10.1016/j.lfs.2005.09.012>
  • Larsen Thomas O., Smedsgaard Jørn, Nielsen Kristian F., Hansen Michael E., Frisvad Jens C.: Phenotypic taxonomy and metabolite profiling in microbial drug discovery. Nat Prod Rep 2005, 22, 672. <http://dx.doi.org/10.1039/b404943h>
  • Buss Antony D., Butler Mark S.: A new model for utilising chemical diversity from natural sources. Drug Dev Res 2004, 62, 362. <http://dx.doi.org/10.1002/ddr.10389>
  • Su Bao-Ning, Jones William P., Cuendet Muriel, Kardono Leonardus B.S., Ismail Rachman, Riswan Soedarsono, Fong Harry H.S., Farnsworth Norman R., Pezzuto John M., Douglas Kinghorn A.: Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2. Phytochemisry 2004, 65, 2861. <http://dx.doi.org/10.1016/j.phytochem.2004.08.007>
  • Eun-Kyoung Seo, Dongho Lee, Young Geun Shin, Hee-Byung Chai, Navarro Hernan A., Kardono Leonardus B. S., Rahman Ismail, Cordell Geoffrey A., Farnsworth Norman R., Pezzuto John M.: Bioactive prenylated flavonoids from the stem bark ofartocarpus kemando . Arch Pharm Res 2003, 26, 124. <http://dx.doi.org/10.1007/BF02976656>
  • Kinghorn A., Farnsworth Norman, Soejarto Djaja, Cordell Geoffrey, Swanson Steven, Pezzuto John, Wani Mansukh, Wall Monroe, Oberlies Nicholas, Kroll David: Novel Strategies for the Discovery of Plant-Derived Anticancer Agents. phbi 2003, 41, 53. <http://dx.doi.org/10.1080/1388020039051744>
  • Minguzzi Sandro, Barata Lauro E.S., Shin Young Geun, Jonas Patrick F., Chai Hee-Byung, Park Eun Jung, Pezzuto John M., Cordell Geoffrey A.: Cytotoxic withanolides from Acnistus arborescens. Phytochemisry 2002, 59, 635. <http://dx.doi.org/10.1016/S0031-9422(02)00022-5>
  • Shin Young Geun, van Breemen Richard B.: Analysis and screening of combinatorial libraries using mass spectrometry. Biopharm Drug Dispos 2001, 22, 353. <http://dx.doi.org/10.1002/bdd.278>
  • Cordell Geoffrey A., Quinn-Beattie Mary Lou, Farnsworth Norman R.: The potential of alkaloids in drug discovery. Phytother Res 2001, 15, 183. <http://dx.doi.org/10.1002/ptr.890>