Pure Appl. Chem., 2000, Vol. 72, No. 3, pp. 343-345
http://dx.doi.org/10.1351/pac200072030343
Chemical etiology of nucleic acid structure
A. Eschenmoser* and R. Krishnamurthy
The Skaggs Institute for Chemical Biology, TSRI, La Jolla, California 92037, USA; Laboratorium für Organische Chemie, ETH, CH-8092 Zürich, Switzerland
Abstract:
The synthesis of potentially natural nucleic acid alternatives and comparison of some of their chemical properties with those of
RNA and
DNA have led to findings that we consider to be relevant in the context of a chemical etiology of nucleic acid structure.