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2012, Vol. 84, Issue 7

Special topic article

Analogue-based drug discovery: Contributions to medicinal chemistry principles and drug design strategies. Microtubule stabilizers as a case in point (Special Topic Article)
Mohammad H. El-Dakdouki and Paul W. Erhardt
p. 1479 [Details + Abstract] [Full text - pdf 2873 kB]

23rd International Conference on Heterocyclic Chemistry (ICHC-23), Glasgow, UK, 31 July–4 August 2011

This conference is part of the Heterocyclic Chemistry series.
Preface
Colin Gibson
p. iv [Details] [Full text - pdf 76 kB]
Targeting neurodegenerative diseases: Drug discovery in a challenging arena
Magid Abou-Gharbia and Wayne Childers
p. 1543 [Details + Abstract] [Full text - pdf 1331 kB]
An acyl-Claisen approach to the synthesis of lignans and substituted pyrroles
David Barker, Benjamin Dickson, Nora Dittrich and Claire E. Rye
p. 1557 [Details + Abstract] [Full text - pdf 665 kB]
Spiroketals: Toward the synthesis of 39‑oxobistramide K
Malgorzata Commandeur, Claude Commandeur and Janine Cossy
p. 1567 [Details + Abstract] [Full text - pdf 793 kB]
Designer chiral phase-transfer catalysts for green sustainable chemistry
Keiji Maruoka
p. 1575 [Details + Abstract] [Full text - pdf 721 kB]
Influence of the difluoromethylene group (CF2) on the conformation and properties of selected organic compounds
David O'Hagan, Yi Wang, Maciej Skibinski and Alexandra M. Z. Slawin
p. 1587 [Details + Abstract] [Full text - pdf 574 kB]
Stereoselective construction of 5,11‑methanomorphanthridine and 5,10b‑phenanthridine structural frameworks: Total syntheses of (±)-pancracine, (±)‑brunsvigine, (±)-maritidine, and (±)-crinine
Ganesh Pandey and Smita R. Gadre
p. 1597 [Details + Abstract] [Full text - pdf 2384 kB]
New strategies for natural products containing chroman spiroketals
Jason C. Green, G. Leslie Burnett, IV and Thomas R. R. Pettus
p. 1621 [Details + Abstract] [Full text - pdf 951 kB]
Radical azidation reactions and their application in the synthesis of alkaloids
Guillaume Lapointe, Ajoy Kapat, Karin Weidner and Philippe Renaud
p. 1633 [Details + Abstract] [Full text - pdf 525 kB]
Total synthesis of gelsemoxonine
Jun Shimokawa, Takaaki Harada, Satoshi Yokoshima and Tohru Fukuyama
p. 1643 [Details + Abstract] [Full text - pdf 648 kB]
Chiral 2,6-bis(5',5'-diphenyloxazoline)pyridine as an efficient ligand for asymmetric catalysis
Pradeep K. Singh and Vinod K. Singh
p. 1651 [Details + Abstract] [Full text - pdf 502 kB]
Dynamic boronic acid-mediated autoligation of DNA strands
Michael Smietana, Anthony R. Martin and Jean-Jacques Vasseur
p. 1659 [Details + Abstract] [Full text - pdf 490 kB]

IUPAC Technical Reports and Recommendations

Names and symbols of the elements with atomic numbers 114 and 116 (IUPAC Recommendations 2012)
Robert D. Loss and John Corish
p. 1669 [Details + Abstract] [Full text - pdf 57 kB]